SPOILERS! Read at your own risk.
Yes. There is an after-credits scene at the end of X-Men: Apocalypse. According to Bleeding Cool:
We see a besuited man walking through the remains of the Weapon X clean-up programme, removing the blood, bodies and bullets. And a suited man retrieving vials of Wolverine’s blood labelled Weapon X. And placing them into his briefcase which contains other vials of differing colours. Slamming shut, it is labelled ESSEX CORP.
For anyone unfamiliar with Essex Corp., the man walking through what remains of Weapon X is Nathaniel Essex. He’s more commonly known as Mr. Sinister, the world’s greatest geneticist who is capable of cloning, creating, enhancing, and controlling mutant abilities. In the comics, he was genetically mutated by Apocalypse. If everything else didn’t scream BAD GUY to you, being genetically mutated by a mutant god should clue you in on which spectrum this guy stands.
Source: Bleeding Cool
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